1.What the tool can do for you?
The eTRIKS Harmonization Service (eHS) is a new addition to the eTRIKS platform that addresses
the needs of eTRIKS current and prospective users for data harmonization and support for cross-study
data investigations across translational research projects.
These extensions include a new standards compliant repository (BioSPEAK-DB) for storing,
sharing and querying harmonized translational research data based on a new generic semantic data
model.
This model builds upon already existing standard initiatives in clinical and pre- clinical data
management,
namely the CDISC and ISA standards to facilitate standard-based data harmonization.
This repository and associated interfaces will facilitate the configuration of study designs,
preparation
of study data for system import and transformation of study data into semantically consistent
representations.
Complimentary to the data repository, a metadata registry is setup part of the eHS to support data
curation
and harmonization procedures, and a new eHS-tranSMART pipeline that improves data loading into
traSMART by
leveraging study-specific configurations generated within the EHS to extract, transform and load
user-selected data
to tranSMART with minimal curator intervention.
